Fluorescence Imaging
Multi-channel epi-fluorescence with LED or laser excitation
openUC2 enables affordable, modular fluorescence microscopy. Use LED or laser excitation sources, user-swappable dichroic mirror cubes, and emission filters — all in the standardized UC2 cube format. Capture multi-channel images with GFP, DAPI, RFP, and custom filter sets. The FRAME microscope supports automated multi-tile fluorescence scanning with stitching.
Technical specifications
| Excitation sources | LED (405/470/530/590/630 nm) or diode laser |
|---|---|
| Filter cubes | Modular UC2 cubes, user-swappable |
| Emission filters | Standard 25 mm diameter, mounted |
| Channels | Up to 5 simultaneous (with motorized filter wheel) |
| Objectives | 4x to 100x, infinity-corrected (RMS/M25) |
| Camera | USB3 or CSI (CMOS) |
Key capabilities
Multi-channel acquisition
Switch between fluorescence channels with motorized filter wheels or manual cube swaps.
Automated tile scanning
Scan large areas with FRAME's motorized stage and stitch tiles into high-resolution mosaics.
LED & laser excitation
Choose LED for safety and broad illumination, or laser for higher intensity and structured illumination.
Open filter design
Use standard 25 mm filters. No proprietary filter cubes — buy from Chroma, Thorlabs, or any supplier.
On the roadmap
Interested in fluorescence imaging?
Tell us about your imaging needs and we'll help you find the right configuration.