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Histology & Slide Scanning

Automated whole-slide scanning with stitching

Turn your openUC2 FRAME into a digital pathology slide scanner. Automated XYZ stage movement captures overlapping tiles across the full 130x90 mm travel range, then stitches them into a seamless whole-slide image. Process H&E, IHC, or special stains at 10x-40x magnification with consistent Koehler illumination. Postprocessing will be available soon. Raw Images e.g. as OME.TIF or OME.Zarr or simply individual Tif images can be exported immediately.

Histology & Slide Scanning application example

Technical specifications

Scan areaUp to 130 x 90 mm (full stage travel)
Resolution10x to 40x objectives
IlluminationTransmitted white LED, Koehler-capable
StitchingAutomated overlap and alignment in ImSwitch
FocusSoftware autofocus per tile
OutputTiled TIFF, OME-ZARR, or pyramidal formats

Key capabilities

Full-slide coverage

Scan up to 130x90 mm — enough for standard glass slides and multiple sections.

Automated tile stitching

ImSwitch captures overlapping tiles and assembles them into a seamless image.

Software autofocus

Contrast-based autofocus runs per tile, maintaining sharpness across uneven sections.

Digital pathology output

Export in standard formats (OME-ZARR, pyramidal TIFF) for use in QuPath, OMERO, or custom viewers.

On the roadmap

AI-based tissue detection for smart scanning
Integration with QuPath export pipeline
Darkfield and polarization imaging modules

Interested in histology & slide scanning?

Tell us about your imaging needs and we'll help you find the right configuration.