Life Science Workflows
Multiwell Screening (96/384-well)
Automated high-content screening on standard microplates
Use FRAME as an affordable high-content screening platform. Automated XYZ stage scans standard 96-well or 384-well microplates, capturing brightfield or fluorescence images at each well. ImSwitch scripting enables custom acquisition patterns, multi-channel imaging, and on-the-fly analysis.
Technical specifications
| Plate formats | 96-well, 384-well (adapter-dependent) |
|---|---|
| Imaging modes | Brightfield, fluorescence (multi-channel) |
| Throughput | 96-well plate: ~10 min (single site/well, 10x) |
| Autofocus | Software-based, per-well |
| Z-stacks | Configurable step size and range |
| Scripting | Python / REST API for custom workflows |
Key capabilities
Standard microplate support
Use off-the-shelf 96-well and 384-well plates with the included adapter.
Multi-site per well
Capture multiple fields of view per well for better statistical sampling.
Script-driven workflows
Program custom plate scanning patterns, channel sequences, and analysis pipelines in Python.
Integration-ready
REST API and SiLA2 enable integration with liquid handlers and robotic plate loaders.
On the roadmap
On-the-fly cell counting and confluence measurement
Integration with CellProfiler analysis pipelines
384-well high-density scanning optimization
Interested in multiwell screening (96/384-well)?
Tell us about your imaging needs and we'll help you find the right configuration.